INano™ HT-Smart
End-to-End High-Throughput mRNA/LNP Screening Workstation
INano™ L+
Rapid Nanomedicine Preparation System
INano™ Optimux
Medium-Scale Formulation (Reusable System & GMP Compliant)
INano™ S
Commercial LNP Manufacturing System
Cell Transfection Kit
Application Kit
Organ-specific Targeting Kit
Validation Kit
DNA-LNP Kit
Protein-LNP Kit
Rui Zhang, PhD
Co-Founder & CEO
As a scientist at heart with a strong passion for improving human health, Dr. Rui Zhang founded XGen with the goal of democratizing LNP technology and accelerating the development of nucleic acid therapeutics.
As an LNP expert who began working on the technology long before it became widely recognized, Rui deeply understands the challenges associated with its applications. At XGen, Rui and his team are developing advanced tools to address some of the most scientifically challenging problems faced by their customers. Rui believes the LNP mixing technology developed at XGen will support researchers at all stages, from discovery to GMP, ultimately helping to create better medicines for patients in need.
Rui earned his PhD at the University of Missouri and completed a postdoctoral fellowship at the University of Pennsylvania. He previously held leadership positions at Spark Therapeutics (acquired by Roche) and Tessera Therapeutics. Rui is the author of over 15 publications in RNA therapeutics, gene delivery, and immuno-oncology, and he is listed as an inventor on more than 15 patent applications. Several of his inventions have been licensed to biotech and pharmaceutical companies for applications in LNP and gene therapy.
Zhenghong Gao, PhD
Executive Scientific Advisor
Dr. Zhenghong Gao is a distinguished scientist and strategic leader with over 15 years of experience in biomedical research and drug development. He specializes in precision delivery technologies (nanoparticle etc.) for large molecules like RNA, DNA, peptides, and conjugates, focusing on developing breakthrough therapeutics for diseases in the areas, such as central nervous system, gastrointestinal tract, and urinary tract, etc.
Dr. Gao has held leadership roles at Bayer’s AskBio, Michigan Medicine, and several Biotech Startups, contributing to multiple innovation and flagship strategic collaboration programs with leading industry partners, Investigational New Drug (IND) applications and First-In-Human (FIH) clinical trials. He has received multiple awards, including the Therapeutic Idea Award for ALS from the Department of Defense.
Dr. Gao has published over 40 articles in journals including Nature Nano, JACS and ACS Nano etc. He is a keynote speaker at various forums. He earned his Ph.D. from the University of Tokyo and trained at leading institutions like CNRS. Previously, he was a Principal Investigator and Assistant Professor at the University of Texas at Dallas, affiliated with UT Southwestern Medical Center.
Stephanie Chun
Field Application Scientist (East Coast, US)
Hello! I am a graduate of Northeastern University (Go Huskies!) with a background in Bioengineering and Biochemistry. I serve as a Field Application Scientist at XGen, covering Boston and the surrounding areas.
Matteo Massaro, PhD
Field Application Scientist (Southwest Region, US)
I am a scientist with a Master's in Medical Biotechnology and a PhD in Material Sciences from a joint program between the Houston Methodist Research Institute and the Chinese Academy of Sciences. My research focuses on drug and gene delivery, particularly RNA therapeutics. Outside work, I enjoy walking my dog, soccer, reading, and cooking. I'm passionate about theatre and sports, which inspire my creativity. At XGen, I serve as a Field Application Scientist covering the Southwest region.
Bubacarr J.B. Touray, PhD
Field Application Scientist (US)
Bubacarr J.B. Touray specializes in RNA biology and vaccine development, with extensive experience in molecular biology techniques and project management. He has published multiple peer-reviewed articles and is actively involved in developing innovative nucleic acid vaccines targeting infectious diseases.
Xiaolei Li
Manager, LNP Formulation
I am a research scientist with a master's degree in chemical engineering from the University of Missouri. I have over five years of experience conducting research in the biomedical field, gained through my work at Massachusetts General Hospital and Cincinnati Children's Hospital. My research focuses on the development of biomaterials and biosensors, which has led to multiple publications. Currently, I serve as a Manager for LNP Formulation at XGen.
